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The Inbetweeners star James Buckley reveals he has been diagnosed with a genetic disease and is overhauling his lifestyle due to being ‘at high risk of a cardiovascular incident’

by LJ News Opinions
August 10, 2026
in Entertainment
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The Inbetweeners star James Buckley has revealed he has been diagnosed with a genetic disease. 

The actor, 38, said he underwent a health check after his wife Clair was taken to hospital in an ambulance suffering from severe dehydration. 

James then asked doctors for further tests after a blood test he had done previously highlighted concern. 

In this week’s episode of The Buckleys podcast, James revealed he is at risk of cardiovascular incident due to having high Lipoprotein(a), a genetically inherited type of blood cholesterol, and has had to give up drinking and cut down on takeaways. 

It promotes faster plaque buildup in arteries, increases inflammation and increases the risk of blood clotting. 

It affects roughly one in five people worldwide, typically presenting no physical symptoms until a cardiovascular event occurs. 

The Inbetweeners star James Buckley has revealed he has been diagnosed with a genetic disease

James revealed he is at risk of cardiovascular incident due to having high Lipoprotein(a), and has given up drinking and cut down on takeaways

 James revealed he is at risk of cardiovascular incident due to having high Lipoprotein(a), and has given up drinking and cut down on takeaways

He explained: ‘I’ve also had health problems as well. It’s something to do with my Lipoprotein(a), something to do with that.

‘There’s nothing you can do about it, by the way. And the doctor’s just been like, “you need to change”.’ 

James has given up drinking for the time being and overhauled his diet. 

He went on: ‘I’m at a high risk now for a cardiovascular incident. My heart, my arteries. I’m not a religious man, but sometimes I feel like there is a God that sort of goes “that’ll teach you”. 

‘I feel like I’ve been on this podcast slagging people off that don’t drink. Yeah, we have boring stuff. And now I’ve been told to try not [laughter] in rein it in [sic].

‘But I’m going to have a beer soon.’

James added he is also worried because it’s genetic that their two sons may have inherited it. 

The actor, 38, said he underwent a health check after his wife Clair was taken to hospital in an ambulance suffering from severe dehydration

The actor, 38, said he underwent a health check after his wife Clair was taken to hospital in an ambulance suffering from severe dehydration

It comes after reports a new Inbetweeners movie is on the horizon – with all four core members of the cast set to return.

The show became an instant classic when it aired for three seasons between 2008 and 2010, with two film spinoffs made as well.

While there have been whispers in the past about a reboot, The Sun has now claimed that the four main actors, namely Simon Bird, Joe Thomas, James Buckley and Blake Harrison, have all signed on the dotted line to star in a third movie for Netflix.

However, the newspaper also said that streaming bosses aren’t satisfied with just the main men returning – they also want to see Emily Atack, 36, reprise her role as Charlotte ‘Big Jugs’ Hinchcliffe.

The move comes as a surprise after Emily was axed from the Inbetweeners reunion five years ago following a ‘past fling’ with James.

A source told the publication: ‘The creators of the show have written the script and are ready to roll – but Emily is one of the missing pieces in the project they’re keen to get in place.

‘Fans will already be delighted that the four main leads are returning as there was concern that a reboot might see new, younger actors cast in the roles of the lads, who were all supposed to be teenagers in the show.

‘But it’s fair to say getting Emily back would be the cherry on the Inbetweeners cake.’

The Sun added that all four of the main actors were ‘thrilled’ to be asked back, but noted that things would be a bit harder for Emily to commit to a reboot movie considering everything she’s got going on at the moment.

Joe Thomas, Simon Bird, James and Blake Harrison have all signed on the dotted line to star in a third movie of The Inbetweeners for Netflix

Joe Thomas, Simon Bird, James and Blake Harrison have all signed on the dotted line to star in a third movie of The Inbetweeners for Netflix

Streaming bosses aren't satisfied with just the main men returning - they also want to see Emily, 36, reprise her role as Charlotte 'Big Jugs' Hinchcliffe

Streaming bosses aren’t satisfied with just the main men returning – they also want to see Emily, 36, reprise her role as Charlotte ‘Big Jugs’ Hinchcliffe

In 2019, Emily was reportedly axed from the Inbetweeners reunion after James told producers ‘it’s her or me’ following a past fling they had when they were both single.

Reports suggested at the time that James was afraid his wife Clair would find out about the brief relationship they had during their days in the show during 2008 to 2010.

As well as starring in Disney series Rivals, Emily is in the process of making a new programme for the BBC called Reputation.

She’s also waiting to find out whether or not ITV will commission a second series of Nobody’s Fool – the game show she hosts with Rivals castmate Danny Dyer.

If filming on the Inbetweeners kicks off soon, the results could air as early as 2027, the source added.

Emily has been asked about a potential Inbetweeners return on numerous occasions in the past, telling Capital FM recently: ‘I don’t know. We’d all be quite a lot older now.

‘What was quite funny was when we filmed the series I was only 17, I’d just left school, but the boys were well into… I think they were in their late twenties, early thirties.’

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Tags: dailymailJames Buckleytvshowbiz
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